團(tuán)隊人員

1.  研究組長：陳江帆教授，美國波士頓大學(xué)醫(yī)學(xué)院教授，研究生導(dǎo)師。1987至1992年在第三軍醫(yī)大學(xué)獲創(chuàng)傷外科學(xué)博士學(xué)位；1987至1993年在賓夕法尼亞醫(yī)學(xué)院獲藥理學(xué)博士學(xué)位；1993至1995年在紐約大學(xué)石溪分校獲藥理系博士后；1995至1997年在哈佛大學(xué)醫(yī)學(xué)院（麻省總醫(yī)院神經(jīng)科），博士后；1997至2000年獲美國哈佛大學(xué)醫(yī)學(xué)院，麻省總醫(yī)院神經(jīng)系，講師；2000至2001年獲美國哈佛大學(xué)醫(yī)學(xué)院，麻省總醫(yī)院神經(jīng)系，助理教授；2001至2002年獲美國波士頓大學(xué)，醫(yī)學(xué)院神經(jīng)系，助理教授；2003至2010年獲波士頓大學(xué)醫(yī)學(xué)院神經(jīng)系，副教授 ；2010至2015獲波士頓大學(xué)醫(yī)學(xué)院神經(jīng)系，教授；2012至2015在溫州醫(yī)科大學(xué)附屬眼視光醫(yī)院擔(dān)任教授（兼職）；2016至今在溫州醫(yī)科大學(xué)附屬眼視光學(xué)院擔(dān)任教授（全職）。獨(dú)立承擔(dān)研究大腦中化學(xué)物質(zhì)多巴胺和腺苷在帕金森氏癥發(fā)病機(jī)制藥理治療研究超過15年。在腺苷領(lǐng)域已發(fā)表超過150篇文章，近五年也發(fā)表過50余篇文章。他還被邀擔(dān)任美國健康研究員基金評委，奧地利科研基金評委，并先后二次在國際學(xué)術(shù)會議上擔(dān)任分會主席。

實(shí)驗室目前擁有國家自然科學(xué)基金重點(diǎn)項目1項，國家重點(diǎn)研發(fā)計劃“重大慢性非傳染性疾病防控研究”重點(diǎn)專項“帕金森病早期診斷生物標(biāo)記及綜合診斷指標(biāo)體系研發(fā)”項目（參加）；國家自然科學(xué)基金青年項目4項；浙江省自然科學(xué)基金一般項目1項；浙江省自然科學(xué)基金青年基金項目3項；溫州市科學(xué)技術(shù)局公益性科技計劃項目4項

2.  工作人員：李智慧、任湘鵬、高英、周建宏、張莉平、鄭武、郭衛(wèi)、王琴、Sergii Vakal、張書雅、何艷、陳行軍、葉芬芬

研究方向

  1. 腺苷A2A受體控制認(rèn)知：工作記憶

  2. 腺苷A2A受體和帕金森病

  3. 腺苷A2A受體控制小膠質(zhì)細(xì)胞/突觸修剪

  4. 腺苷A2A受體控制認(rèn)知：認(rèn)知可塑性

  5. 腺苷A2A受體對腦機(jī)接口控制

  6. 腺苷A2A受體和神經(jīng)膠質(zhì)瘤治療

  7. 腺苷A2A受體對腦機(jī)接口控制

  8. 腺苷A2A受體對視網(wǎng)膜血管化調(diào)控

  9. 腺苷A2A受體控制認(rèn)知：操作性行為

Laboratory of Molecular Neuroscience

Team members

1.  Principle Investigator: Jiang-Fan Chen, MD, PhD

Jiang-Fan Chen was awarded as National "Thousands of People Plan" innovative talents. He obtained his Ph.D. degree in Traumatized Science from Third Military Medical University in 1992. He obtained his Ph.D. degree in Pharmacology from Pennsylvania medical school in 1993.From 1993-1995, he got training as a postdoctoral follow in Dept. Pharmacology, SUNY at Stony Brook (with C. M. Malbon),then from 1995-1997 he got training as a postdoctoral fellow in Dept. Neurology, Mass. Gen. Hospital/Harvard Med. Sch. (with JS. Fink).During 1997-2000, he was the instructor of Neurology in Harvard Medical School and in 2001 he became an assistant professor in Department of Neurology in Harvard Medical School, USA. From 2001 to 2002, he worked as an assistant professor in Department of Neurology, Boston University School of Medicine, then from 2003-2009 he worked as an associate professor in Department of Neurology, Boston University School of Medicine, USA. From 2010, he worked as a Professor in Department of Neurology, Boston University School of Medicine, USA. He joined the Eye Hospital, Wenzhou Medical University in 2011 as a Principal Investigator. He independently undertook to study the pharmacological treatment of dopamine and adenosine in the brain for more than 15 years in the pathogenesis of Parkinson's disease. More than 150 articles have been published in the field of adenosine, and more than 50 articles have been published in the last five years. He was also invited to serve as the judge of the health research fund of the United States, the Austria scientific research fund, and as the chairman of the international academic conference two times.

2.  Team Staff: Zhihui Li, Xiangpeng Ren, Ying Gao, Jianghong Zhou, Liping Zhang, Wu Zheng, Wei Guo, Qin Wang,  Sergii Vakal, Shuya Zhang, Yan He, Xingjun Chen, Fenfen Ye

Scope of Research Proposal

1. Adenosine A2A Receptor control cognition: working memory

2. Adenosine A2A receptor and Parkinson's disease

3. Adenosine A2A receptor controls microglia / synaptic pruning

4. Adenosine A2A receptor control cognition: cognitive plasticity

5. Adenosine A2A receptor is controlled by the brain machine interface

6. Adenosine A2A receptor and glioma treatment

7. Adenosine A2A receptor is controlled by the brain machine interface

8. Adenosine A2A receptor regulates the vascularization of the retina

9. Adenosine A2A receptor controls cognition: operational behavior